Kategóriák: Minden - databases - genes - proteins - organisms

a nurul aisyah 10 éve

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DATABASES

The document provides a comprehensive overview of various specialized databases organized under different categories related to biological and genetic research. It includes microarray and gene expression databases like HemBase and Gene Expression Barcode, immunological databases such as Epitome and the MUJEN Mouse Database, and protein sequence databases including Patome and UniProt.

DATABASES

DATABASE Group member: Nurul Aisyah Afifah Liyana Noor Atiqah Norfariza Ronalizah

Different Type of Databases

To find out the protein domain, sequences features and 3D structures

InterPro

CATH

Database of Carbohydrate-Active enzymes which contains classification and associated information about enzymes involved in the systhesis, metabolism and transport of carbohydrates.

CAZypedia

Database of protein families that include annotation and multiple sequences aligments generated using hidden Markov models
Database resources for understanding high level function and utilities of the biological system

KEGG DRUG

KEGG DISEASES

KEGG GENES

KEGG GENOME

Database of protein sequences and functional information

UniParc

UniRef

UniProtKB

Organization of Databases in NAR

Cell Biology
CloneDB
NCBI BookShelf
Immunological Databases
MUJEN MOUSE DATABASE
Epitome
General Plant Databases

PGDD

GeneFarm

Chloroplast Genome Database
Organelle Databases
Metochondrial Genes and Protein

HMPD

MITOMAP

GOBASE
Organelle Genome
Molecular Biology Databases
Molecular Probe and Primer

VirOligo

PrimerBank

Drug and Drug Design

PharmGed

CellFinder
PubMed
Network Portal
Proteomics Resourses
MAPU
MOPED
GELBANK
Microarray Data and Other Gene Expression Databases
Sebida
HemBase
Gene Expression Barcode
Human Genes and Diseases
Cancer Gene Databases

CancerGene

MethyCancer

Protein Mutant Database
CancerResource
Human and Other Veterbrate Genomes
Human Genome Database, Maps Viewers

HOWDY

GeneAnnot

Model Organisms, Comparative Genomics

GeneSpeed

AgBase

Metabolic and Signalling Pathway
Enzyme and Enzyme nomeclature

ORENZA

BRENDA

Protein-protein Interaction

GeneNet

IBIS

ChemProt
Genomic Databases ( Non-Vertebrate)
Viral Genome Databases

ViralZone

HFV Database

The Gene Indices
MGD-mouse genomic database
Structure Databases
Protein Structure

Genome3D

DBAli

Small Molecule

DrugBank

SuperDrug

BARD
Protein Sequence Databases
Protein Properties

Cybase

REFOLD

General Sequence Databases

UniProt

RNA sequence Databases
snOPY
MeRNA
BPS
Nucleotide Sequence Databases
Transcriptional Regulator Sites and Transcription Factors

3D-Footprint

Gene Structure, introns and exon, Splice side

ECgene

GeneTack

Coding and Non-coding DNA

Patome

Dfam

International Nucleotide Sequence Database Collaboration

GenBank

BioSample

New and Updated NAR Database

Others Molecular Biology Databases
Plant Databases
Genomic Variation, Diseases and Drugs
Progenetix
NECTAR
Lynx
HbVar
FINDbase
DriverDB
canSAR
Database of Genomic Variant (DGV)
Sanger institute's DECIPHER

database of pathogenic single nucleotide variant, indels and copy-number variant

NHGRI GWAS Catalog

a curated resources of SNP-Treat Association

NCBI's ClinVar

database documenting clinically relevant sequences variant

Human Genome, Model Organisms, Comparative Genomics
Model Organism Databases

International Mouse Phenotyping Consortium (IMPC)

Vertebrate Genome Annotation (VEGA)

Mouse Phenome Database

Mouse Gene Expression Database

Mouse Genome Database (MGD)

FlyBase

WormBase

Saccharomyce Genome Database (SGD)

Human Genome

Consensus CDS Project

collaborative effort to identify a core set of human protein region

dbGaP

related to clinically relevant phenotype

database of genotyping result

Viruses, Bacteria, Protozoa and Fungi
Taxonomic

MetaRef

Sequence of Microbial Genome

BacDive

the SILVA/LTP project

Ribosomal Database Project (RDP)

Microbial Diversity in Natural Enviroment

EBI metagenomics resources

JGI'S IMG/M

Genome Annotation

Free-living Microorganism

SubtiWiki

Rhizobase

PortEco

CynoBase

Human Pathogen

SEED

PATRIC

IMG

Human Microbiome Project
Metabolics and Signalling Pathways, Enzymes, Protein Modification
Metabolics Pathway Databases

MultiTaskDB

EKPD

Merops

Carbohydrate-Active enzyme Database (CAZy)

Structure-Function Linkage Database (SFLD)

Catalytic Site Atlas

Small Molecule Pathway

Reactome

MetaCyc

Protein Sequences and Structure, Motifs and Domains, Protein-protein Interactions
protein-protein interaction

Protein SCOP Database

SCOP2

SCOP Hierarcy

SCOPe

Negatome database

NCBI (MMDB)

calculated using VAST +

protein structure database

RDBe

analysis of the electron microscopy derived structure

visualization

structural database

RNA bricks

NDB

2 new database

Repeats database

HRAP

annual update

popular database

ELM

eggNOG

uniprot and KEGG

Nucleic Acid Sequence and Structure, Transcriptional Regulation
Transcription Factor Binding Sites (TFBSs)

YEASTRACT

JASPAR

NONCODE Database

Various type of non-coding RNA

microRNA Databases

starBASE

PolymiRTS

mirTarBase

miRNEST

miRBase

Criteria that need to be fulfilled to be inserted into NAR database

Can be access without interface or paywall
must update regularly
discuss the topic of interest
Molecular biology
Structural biology
RNA

new information about the structure and biochemistry of nucleic acid binding proteins or enzymes that function in RNA metabolism

Structure,biogenesis,cellular roles and regulation of non-coding RNAs

structure assembly,mechanism of action and regulation of ribosomes,snRNPs and other stable ribonucleoprotein particles

nucleic acid enzymes
genomics
genome integrity,repair and replication
Gene regulation,chromatin and epigenetics
Computational biology

Describe the use of existing computational method to generate significant novel biological information

Description of a new algorithm that represents a substantial improvement over current methodology and has direct biological relevance

synthetic Biology and Chemistry
emerging or specialized subject areas

single molecule studies of macromolecular function

molecur machines and complex molecular assemblages

genome studies using massive parallel(Deep) sequencing

gene targeting and Genome Engineering

nuclear architecture and functional consequences

single cell gene regulation studies

Importants of Databases

Gene3D
to study the 3D structure of protein and each sequences of the structure
CAZy
determine in detailed the activity and metabolism of our protein towards carbohydrate
Pfam
can study the structure and alignment of protein
contain the family tree our protein
KEGG
study the whole function our protein
to find out the detail of biological activities of our protein
Uniprot
analyse the functional information of the protein
important to find out the sequences of our protein