Kategóriák: Minden - barriers - absorption - pharmacokinetics - metabolism

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Drug Administration-psg

The text discusses various aspects of drug administration and the factors influencing their effectiveness in the body. It delves into pharmacokinetics, detailing the processes of disintegration, dissolution, and distribution of drugs, including the roles of different barriers like blood-brain and placental barriers.

Drug Administration-psg

Drug Administration

Biopharmaceutics

Gas
Ex: Oxygen, Anesthesia, Aerosol Inhalers
Liquid
Suspension
Emulsion
Solution
Solid
Suppositories (Inserts)

Vaginal

Rectal

Troches

Pastille

Lozenge

Capsules

Soft Gelatin

Hard Gelatin

Tablets

Buccal (Sublingual)

Effervescent

Controlled release

Multiple Compressed

Enteric coated

Film coated

Sugar coated

Compressed

Pharmacokinetics

Disintegration and Dissolution
Metabolism (Biotransformation)

Intestinal Mucosa

Lungs

Kidneys

Liver

Conjugation

Oxidation, Hydrolysis, or Reduction

Distribution

BARRIERS

Placental Barrier

Blood-Brain Barrier

Factors

Drug Reservoirs

Bone Tissue

Fat Tissue

Plasma

Regional Blood Flow

Cardiac Output

Absorption

Compatibilty

Lipophilicity

Acid-Base Properties

Concentration

Blood Flow

Surface Area