From the mid-17th century to the mid-20th century, significant advancements in microbiology marked the First Golden Age of the field. Key figures made groundbreaking discoveries that laid the foundation for modern science.
Proposed a model for the structure and replication of DNA.
1950's
Transposons- are tiny segments of DNA that can move from one region of DNA molecule to another
A geneticist who discovered transposms in corn.
Barbara McClintock
1940's
George W. Beadle and Edward I. Tatum
demonstrated the relationship between genes and enzymes
Main topic
1928
Accidently discovered penicillin, first antibiotic discovered
Alexander Fleming
1910
Paul Ehrlich
Discovered first treatment for syphilis
1884
Discovered Phagocytosis. Observed cells collected around a splinter inserted in a sea star embryo
Elie Metchnikoff
1876
Discovered Anthrax -Bacillus anthracis(not the band)
1864
Created pasteurization
Demonstrated that microbes in the air could contaminate sterile solutions, but the air itself can not create microbes. Showed microbes could be present in non living matter and could be killed by heat.
Louis Pasteur
1847
Ignaz Semmelweis
Proved that microorganisms causes surgical would infection
1843-1910
4.The pathogen must be isolated from the inoculated animal and must be shown to the original organism.
3. The pathogen from the pure culture must cause the disease when it's inoculated into a healthy, susceptible laboratory animal.
2. The pathogen must be isolated from the diseased host and grown in pure culture.
1. The same pathogen must be present in every case of the the disease.
Koch's Postulates.
Robert Koch
1827-1912
Joseph Lister
Treated surgical wounds with phenol which killed bacteria, decreased infection and death in patients. Responsible for aseptic techniques. (Listerine)
1796
Created the first vaccine for small pox. Inoculated people with a similar virus – cow pox.
Edward Jenner
1753
Carl Linneaus
Developed the binomial nomenclature that we use today.
1673-1723
first person to observe living organisms under a microscope he called them Animalcule (microorganism)
Anton Van Leeuwenhoek
1668
Francisco Redi
Did not believe in spontaneous generation, he experimented with meat in jars to prove maggots did not arrive spontaneously
1665
Looked at a cork under a microscope and saw boxes which he called cells.
