Categories: All - toxicity - pharmacodynamics - mechanisms - interactions

by Juan Longoria 15 years ago

1441

Pharmacodynamics

The study of pharmacodynamics encompasses understanding how drugs interact with the body, including both specific and nonspecific interactions. It delves into how drugs can either stimulate or block biological processes through interactions with enzymes or receptors, where the concepts of agonists and antagonists come into play.

Pharmacodynamics

Pharmacodynamics

therapeutic index

TI = LD50 / ED50
effective dose
lethal dose

half - life elimination

50% of drug

drug - drug interaction

chemical incompatibility
synergism

adverse effects

good or bad
no safe drug
allergic reaction
toxicity

drug - response relationships

serum concentration - time profile
therapeutic range
toxic level
peak serum concentration
minimum effective concentration
duration of action
termination of action
onset of action or latent period
potency
efficacy

mechanisms of action

nonspecific drug interactions
drug - enzyme interactions
stimulation or blockage occurs
drug - receptor interactions
antagonist
agonist
affinity