CH 13,14,16

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Crystallography

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CH 13,14,16

Gene Regulation

Activate the protein

Postranslational Control

Translational Control

Posttranscriptional control

Enzyme Regulation

Some human disorders involve enzyme defects

Lactose induces Transcription of the lac operon

Operon

Transcriptional level control

Translate RNA to form protein

Transcribe gene to form RNA

Human Genetics and the Human Genome

DNA

Pedigree

Result from Chromosomal error

XXY karyotype

Turner Syndrome

Down syndrome

Chromosomal analysis and genomic diseases

Abnormal chromosome Breaks

Nondisjunction

Aneuploidies

Disomy

Polyploidy

46 Chromosomes

Karyotype

Gene Expression

Translation

Ribosome translation site

Amino Acids

Transcription

DNA-RNA

Mrna, Rrna, Trna