Genetic Technologies
Genetically Modified Organisms
Explanation
The transfer of genes is possible and easy due to
the fact that most life forms share the same language
of heredity or 'DNA code'.
The technology is called Recombinant DNA Technology
Genetic modification technology
allows genes to be transferred for
acquiring specific traits using laboratory
techniques
Technologies used
Gene gun
Shooting microscopic pellets of gold/tungsten
that are coated in the DNA being transferred
through a particle gun. The specialized bullet
becomes coated with the pellets once fired,
allowing for the pellets to enter the cell at high
speed. Then, cells are grown on a dish if successful.
Insertion through vectors
Agrobacterium tumefaciens's tumour production region
causes unctrollable tumour growth when inserted into a plant.
Positives
Allows our crops to not be
as vulnerable to insects
Allows herbicides to be more
effective on our crops
Benefits the environment
due to decreased use of pesticides.
Negatives
Seen as unethical within society as it is unnatural and still
being explored/researched.
Possible threat to the environment since GMO's are not natural, therefor they clash with the idea of natural growth within the environment
Human Genome Project
Explanation
A global research effort to identify the 30,000 genes in human DNA.
Used to determine the 3 billion different nitrogenous bases
Technologies used
Use a computer that shows the human DNA sequence as a series of coloured bands and each colour represents a base.
Negatives
May decrease human diversity
Could allow weapons to be created that target the population's demographic
Positives
Help with the prevention and identification of diseases
Allow us to modify medicine and make it more effective
Helps with overall understanding of the 'blueprint for a human being'
Assisted with the field of forensics, as it easier to positively
identify someone from extremely small pieces of biological substances
DNA Identification
Explanation
DNA identification is a method used to identify a person.
There are 3 types of testing; parental, forensic and genetic. All of these look for similarities in the genetic markers between 2 samples
Technologies used
Short tandem repeats
regions of non-coding DNA that have
repeats of the same nucleotide sequence
Process includes collecting the sample of DNA
(blood tests, mouth swabs, body tissue, semen),
then extracting the DNA from the nucleus of the cell,
copying the DNA, determining the size of the DNA and
finally seeing if the sample matches with another sample
Finger printing
Often used in criminal cases
Positives
Helps identify biological relations
Identifies suspects or victims in criminal situations
Can test for birth defects or genetic conditions
Find out information on someone's ancestors
Extremely small amounts of DNA can still be extremely useful
Negatives
Seen as unethical as some authorities keep DNA when it is not needed (there is a lot of suspicion around this)
If samples are not stored fast and properly, bacteria can attack the cells that contain DNA
Gene Therapy
Explanation
Technology involves introducing genetic material into a person's cells to help fight or prevent diseases they may face
Vectors are used to deliver a gene to a cell, and
vectors are commonly viruses. Although, these viruses are changed to be safe for humans (there is still some risk)
Technologies used
Somatic gene therapy
ex vivo
Cells are changed outside of the body and
transplanted back in
in vivo
The gene is transferred to cells inside
the host's body
Is safer approach because it affects only the targeted cells in the patient, and is not passed on to future generations
Germ-line gene therapy
The result of this is permanent changes that are passed down to further generations
Positives
Treats diseases for humans and animals
Successful germ line therapy leads to the possibility of eliminating select diseases from a certain family of people
Negatives
Some viral vectors could infect a broader
range of cells than intended
Could lead to cancer since there is a
possibility of disrupting gene regulation
Seen as unethical by many people as it is 'playing God'