Thrombocytopenia

Underproduction

Marrow failure

Myelodysplasia

Aplastic anemia

Vitamin deficiencies

Marrow infiltration

Tumors

Leukemias

Lymphomas

Fibrosis

Granulomatous diseases

Marrow toxins

Drugs

Radiation

Infxn

EtOH

Peripheral destruction

Nonimmune

DIC

TTP

Immune

Drugs

a/w HIV

a/w other auotimmune

ITP (Idiopathic)

Splenic sequestration

Liver dz w/ portal HTN