How Pain Killers work

Mai multe ca aceasta

lvoelker15@yahoo.com

după Lilianne Voelker

NW GQ2 lesson and IR

după Rachel Comfort

Coronavirus Iria and África

după Guglielmetti Fernandez Guglielmetti Fernandez

6g

după jdjdjdjj jfjjfjdj

-Where the pain signal is created

-Paracetamol acts a reducing co-substrate to POX -Works well in low arachidonic acid levels to inhibit POX -In high levels it weakly inhibits POX

-Slows the prostaglandin formation -Inhibits cyclooxygenase (COX) -Blocks nociceptor activation

-Work by bonding to the opioid receptors -Mimic endorphins -Aid with opening of potassium channels -Block the opening of calcium channels -End result is inhibiting the ability to transmit the pain signal

-Signal travels to the cerebral cortex -Travels via Fiber axons -2 kinds of axons -Type A -Type C

- Release of prostaglandin

Paracetamol

-Work similar to NSAIDs by blocking prostaglandin formation -Lack of strong anti-inflammatory effect

-2 step process to form prostaglandin -COX produces prostaglandin G2 from arachidonic acid -Peroxidase (POX) converts to prostaglandin H2

NSAIDs

Opioids

Nociceptors

-Nociceptors releases a signal in the form of action potienal

Modulation

- Where the body interacts with nerves to deal with the pain -Releases endorphins or serotonin

Perception

-Where you become aware of the pain

Transmission

Transduction

4 stages of pain

Different Kinds of pain killers

How pain works

How Pain Killers work