ANTIMICROBIAL CHEMOTHERAPY METHODS - Copy

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Osteomyelitis

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Antibiotics Mechanism

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Target organism

Mode of Action

Origin

Example of Antibiotic

Cidal and static activity

Spectrum of Action

ANTIMICROBIAL CHEMOTHERAPY METHODS

Classification of Antibiotics

General properties of an ideal antibiotic

no allerginicity - the molecule should not cause an alllergic reaction. minimal irritation.

sold at a reasonable cost -it should be cost effective and readily available.

should hve a long shelf life- shoulf not be light,temperature sensitive

bacteria should not develop resistance to the drug

should not harm or eliminate normal flora

Should be efffective in the presences of body fluids and exudates

chemotherapeutic index-the efficacy of the molecule should always overcome the toxic reactions or adverse reactions

the antibiotic should exhibit selective and effective antimicrobial activity

Definition

involve the administration of drugs with selective toxicity agaianst pathogens involved in infectiion , not host cells .