Sickle Cell Anemia By: Cory McConnell

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Symptoms of SCA

Symptoms of SCA include: - Anemia: The Sickle Cells are destroyed by the spleen, and cause a shortage of blood cells. - Yellow tint in the skin: Due to the Sickle Cells being unable to carry oxygen, this causes a yellowish tint in the skin. - Sudden, unexplained pain: The blockages in the blood vessels can cause swelling and pain. - Swelling: Swelling in the abdomen, hands and feet are common, due to blockages.

Sources

Green, E. “About sickle cell disease.” National Human Genome Research Institute (NHGRI), 26 May. 2020, https://www.genome.gov/Genetic-Disorders/Sickle-Cell-Disease

Pecker, Lydia. “Sickle Cell Disease | Sickle Cell Anemia.” MedlinePlus, U.S. National Library of Medicine, 17 Feb. 2021, https://medlineplus.gov/sicklecelldisease.html

Gibbons, Gary H. “Sickle Cell Disease.” National Heart Lung and Blood Institute (NHLBI), U.S. Department of Health and Human Services, 1 Sept. 2020, https://www.nhlbi.nih.gov/health-topics/sickle-cell-disease

“Sickle Cell Anemia: Symptoms, Causes, Treatments.” Cleveland Clinic, 31 May 2019, https://my.clevelandclinic.org/health/diseases/4579-sickle-cell-anemia

Staff, MayoClinic. “Sickle Cell Anemia.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 30 Jan. 2020, www.mayoclinic.org/diseases-conditions/sickle-cell-anemia/symptoms-causes/syc-20355876

Shiel, William C. “21 Sickle Cell Anemia Symptoms, Genetics, Treatment, Life Expectancy.” MedicineNet, MedicineNet, 10 Jan. 2020, https://www.medicinenet.com/sickle_cell/article.htm

Treatments

WARNING: Do NOT take my word for it, I am by no means a doctor. Please consult with a professional about the subject before considering these medications.

If you are experiencing some signs of SCA, consult with your doctor about these Prescriptions: Hydroxyurea, L-glutamine oral powder, Crizanlizumab, Voxelotor. - Please note that these medications are for relieving pain, reducing symptoms and preventing complications. Though not guaranteed, they may potentially even cure SCA in some children and teenagers. (Taken from Mayo Clinic, 2020)

What is Sickle Cell Anemia?

SCA is so bad because the deformed sickle cells are inefficient at delivering oxygen to the rest of the body. The sickle cells can also clog arteries and cause major problems to the rest of the body. The body sends the sickle cells to the spleen, where they are destroyed. This is why you get anemia, because your body can't replace old cells fast enough.

Sickle Cell Anemia (SCA) is a genetic disorder that affects the 11th chromosome, the one responsible for creating proteins. SCA is characterized by the patient having both normal Red Blood Cells, and deformed, misshapen cells. These misshapen are crescent moon or sickle shaped, hence the name of the disorder.