Kategorier: Alla - câncer - tratamento

av Victoria Porto Sandre Missiatto för 3 årar sedan

207

Síndrome de Mama e Ovário Hereditário (HBOC)

A Síndrome de Mama e Ovário Hereditário (HBOC) é caracterizada por um padrão de herança autossômica dominante e está associada a mutações nos genes supressores tumorais BRCA1 e BRCA2.

Síndrome de Mama e Ovário Hereditário (HBOC)

Síndrome de Mama e Ovário Hereditário (HBOC)

The first division between continents was made by ancient Greek navigators, who named them 'landmass, terra firma'.

Generally classified by convention rather than any strict criteria, nowadays seven regions are regarded as continents from a geopolitical point of view.

Tratamentos e Profilaxia

You can find on this continent:

Aconselhamento genético
ooforectomia profiláticas

The world's largest snake and the second-longest lives here.

Name this snake as well as other animals that can be found in South America.

Fármaco olaparib

The largest forest, which covers 30% of South America's total area, is famous for its biodiversity. It’s crisscrossed by thousands of rivers, including the powerful Amazon.

Name this forest as well as its type.

inibidores da PARP (polimerase de poli ADP-ribose)

compromete o funcionamento da via de reparo de danos ao DNA conhecida como BER (Base excison repair)

mastectomia

The world's highest uninterrupted waterfall can be found here.

Write down its name, height and the country in which you can find it.

quimioterapia profilática

There are 12 countries that make up South America.

Name as many of you can! Don't forget about their capitals.

Achados clínicos

North America has five time zones and it is the only continent with every type of climate.

North America was named after the explorer Amerigo Vespucci and is also known as the 'New World'.

The world's largest sugar exporter among the seven continents - Cuba - also called the 'sugar bowl of the world' is located here.

Pacientes maiores de 18 anos, diagnosticados ou não com câncer, independente do sexo, quando houver mutação deletéria em BRCA1 ou BRCA2 conhecida em familiar de 1o, 2o e 3o graus.
Pacientes de origem judaica Ashkenazi
Pacientes com câncer de próstata e ≥ 2 familiares do mesmo lado da família com câncer de mama e/ou ovário e/ou pâncreas ou próstata.
Pacientes com câncer de pâncreas e ≥ 2 familiares do mesmo lado da família com câncer de mama e/ou ovário e/ou pâncreas ou próstata.
Mulheres com diagnóstico atual ou prévio de câncer de ovário em qualquer idade e independente da história familiar.
Diagnóstico de câncer de mama em qualquer idade

The specialty of some animals is they are found only in a particular region and nowhere else in the world. North America is home to many of such amazing animals.

Name at least 6.

≥ 2 familiares do mesmo lado da família com câncer de pâncreas ou próstata
≥ 2 familiares do mesmo lado da família com câncer de mama em qualquer idade
≥ 1 familiar com câncer de ovário em qualquer idade
≥ 1 familiar com câncer de mama masculino em qualquer idade
≥ 1 familiar com câncer de mama feminino em idade ≤ 50 anos
Diagnóstico de câncer de mama eM idade ≤ 60 anos se câncer de mama triplo negativo

Native Americans have lived along this river and its tributaries for thousands of years. Most were hunter-gatherers, but some formed agricultural societies.

Formed from thick layers of the river's silt deposits, this river's embayment is one of the most fertile regions of the United States; steamboats were widely used in the 19th and early 20th centuries to ship agricultural and industrial goods.

Name this river.

Diagnóstico de câncer de mama em idade ≤ 50 anos

The world's largest freshwater lake by surface area and the third-largest freshwater lake by volume can be found here. It provides a route for the transportation of iron ore, as well as grain and other mined and manufactured materials.

Large cargo vessels called lake freighters, as well as smaller ocean-going freighters, transport these commodities across this lake.

Name this lake.

Paciente com história familiar limitada
Um familiar de com câncer de mama, ovário, próstata ou pâncreas.
Um segundo tumor primário da mama
Diagnóstico de câncer de mama em idade ≤ 45 anos.

There are 23 countries that make up North America.

Name as many of you can! Don't forget about their capitals.

Diagnóstico

Of the seven continents of the world, Africa is the second largest.

Africa comprises 54 countries and it is the hottest continent.

The equator passes through the middle of Africa and it receives direct sunlight throughout the year.

The world gets 66% of its chocolate, 50% of the gold and 95% of the diamonds from Africa.

O padrão ouro

What are the major animals found in Africa?
Also, there are a few species that can be found only in Africa.

Name at least 6 of these animals.

Sequenciamento de Sanger

Caso não existir a possibilidade de ser realizado um painel genético por NGS

MPLA (Multiplex Ligation-dependent Probe Amplification)

Detectar grandes duplicações e deleções, que são ignoradas no sequenciamento

realização do painel genético por NGS (sequenciamento de nova geração)

verificar a ocorrência de SNPs (polimorfismo de nucleotídeo único) na sequencia de DNA

análise de pequenas deleções ou inserções

Outros tumores relacionados a sindrome

Asia is the world's largest continent of the seven continents in size, as it covers one-third of the earth's surface.

It includes 50 countries, and it is the most populated continent, 60% of the total population of the Earth lives here.

melanoma
cabeça e pescoço
gástrico

What are the major animals found in Asia?

Name at least 4 of these animals.

vesícula biliar

The only man-made structure that can be seen from space is located here.

Name this construction and add other facts about it.

pâncreas

Asia houses the highest point on earth.
Name this summit and write down how tall it is.

próstata

Name as many as you can out of the 48 countries located in Asia.

Write down the capitals too.

Características gerais

Europe is separated from Asia by the Ural mountains and the Caspian Sea.

It is surrounded by water on three sides: Mediterranean Sea in the south, Atlantic Ocean in the west, and the Arctic Ocean in the north.

Three-fourth of the world's potatoes grow in Europe.

Efeito fundador

Europe has many exceptional animals, birds, and reptiles with unique methods of staying and hunting.

Name at least 4 of them.

Brasil

A proporção de componentes genéticos de cada região pode divergir, devido a grande miscigenação do país.

c.5382insC

gene BRCA1

Portugal

c.156_157insAlu

éxon 3 do gene BRCA2

Polulação judaíca Ashkenazi, Alemanha

Europe is a large region, with several major rivers that connect its many countries. There are five primary rivers in Europe, and one of them flows through 10 countries, more than any other river in the world.

Name these rivers.

617delT
185delAG

5266dupC

Caráter autossômico dominante,

Europe is one of the smallest continents, yet it is home to some of the largest mountain ranges.

About 20% of the total landmass of the continent is considered mountainous.

Name the 5 longest mountain ranges in Europe.

mutações nos genes supressores tumorais

The most beautiful cities in the world can be found in Europe. History, architecture, arts, and famous cuisine is representative almost to each country.

Out of 51 countries how many you can name?
And how many capitals?

BRCA2

27 éxons com 91103 pb e está localizado em 13q12

BRCA1

24 éxons com 81190 pb, está localizado em 17q21