Drugs In The Body
When a drug enters the body, it first reaches the stomach where it begins to dissolve. From there, it travels to the liver where liver enzymes may destroy a significant portion of the drug molecules.
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Drugs In The Body Receptors Medicine does not do its work until it
binds to a TARGET receptor or enzyme. Receptors at the target organ(s)
latch onto the drug molecules. Small Intestine PROBLEMS:
- Molecule must be small enough to make
it through the stomach and/or intestinal
lining. Any remnants of the medicine from
the stomach travel to the small
intestine where they finish dissolving. Cells Biochemical reactions within the cells
produce the desired effects. Cells soak up the medicine and it
begins to work. Enzymes Side effects can happen when drug molecules
bind to receptors or enzymes that are not the target. Medicine does not do its work until it
binds to a TARGET enzyme or receptor. Enzymes in the liver can destroy some
types of molecules which can be a good
thing as you are trying to eliminate the
drug from your body. Enzymes in the stomach
start to dissolve the medicine. Circulatory System All of the organs in the body are supplied
with blood and the medication goes along
with it. Surviving molecules are carried to
the blood stream for distribution. Protein Protein molecules have structure
complementary to those of the drug
molecule. PROBLEM:
- Protein in the bloodstream can highjack
drug molecules, preventing them from
reaching their destination. Liver PROBLEM:
- Liver enzymes may destroy large
portions of the molecule. After the drug is absorbed in the stomach
the drug molecules travel to the liver. Fat PROBLEM:
- Fat in the bloodstream can highjack
drug molecules, preventing them from
reaching their destination. Stomach and
Stomach Acids PROBLEMS:
- Can be destroyed by stomach acids This is why insulin
is injected or inhaled rather
than swallowed as a pill. As medicine enters the body
orally, it travels down to the
stomach where it begins to dissolve. Ways Drugs Can
Enter The Body Transdermal I.V. Injection Inhale Oral
