类别 全部 - synthesis - depression - hallucinations - perception

作者:jay mullen 11 年以前

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Lysergic acid diethylamide

LSD, or lysergic acid diethylamide, is a potent hallucinogenic drug first synthesized by Swiss chemist Albert Hofmann in 1938 at Sandoz Laboratories. The hallucinogenic properties of LSD were not discovered until 1943 when Hofmann accidentally ingested a small amount and experienced intense visual and sensory distortions.

Lysergic acid diethylamide

Lysergic acid diethylamide

negative side effects

Flashbacks, or a recurrence of the LSD trip, often without warning long after taking LSD Severe depression or psychosis
Severe, terrifying thoughts and feelings Fear of losing control Panic attacks
Impaired depth perception Impaired time perception, distorted perception of the size and shape of objects, movements, color, sounds, touch and the user’s own body image
Delusions Visual hallucinations

what is LSD?

Subtopic
It was discovered in 1938 in a fungus that grows on rye and other grains. LSD has a high potential for abuse.
a synthetic crystalline compound, lysergic acid diethylamide, that is a potent hallucinogenic drug.

psychological effects

Of those who have reported experiencing flashbacks, many are also mentally ill. Some doctors suggest that what the user perceives as a flashback is really a form of psychosis or mental illness that may have emerged due to LSD use. There's a medically recognized disorder called Hallucinogen Persisting Perceptive Disorder (HPPD), in which some people who have taken LSD constantly experience visual hallucinations (as opposed to the brief flashbacks).
It has been stated before that LSD remains in the body forever in minuscule amounts in the brain or spinal fluid, but there's no evidence to support this claim. People who believe in it, however, say that the brain holds and may release molecules of LSD over time, and this is what causes flashbacks
It's believed that LSD works similarly to serotonin, a neurotransmitter responsible for regulating moods, appetite, muscle control, sexuality, sleep and sensory perception.

Hw was it found?

Albert Hoffman wrote this about his LSD experience, "Everything in the room spun around, and the familiar objects and pieces of furniture assumed grotesque, threatening forms. The lady next door, whom I scarcely recognized, brought me milk… She was no longer Mrs. R., but rather a malevolent, insidious witch with a colored mask.”
According to a Road Junky writers, "Albert Hoffman deliberately dosed himself [after a milder accidental dose] with just 25 mg, an amount he didn't imagine would produce any effect. Hoffman got on his bicycle and rode home [from the Lab] and arrived in a state of panic. He felt he was losing his grip on sanity and could only think to ask for milk from the neighbors to counter the poisoning."
It was not until 1943 that Albert Hofmann discovered the hallucinogenic properties of LSD. LSD has a chemical structure that is very similar to the neurotransmitter called serotonin. However, it is still not clear what produces all the effects of LSD.
LSD was first synthesized on November 16, 1938 by Swiss chemist Albert Hofmann in Sandoz Laboratories in Basle, Switzerland. However, it was a few years before Albert Hofmann realized what he had invented. LSD known as LSD-25 or Lysergic Acid Diathylamide is a psychoactive hallucinogenic drug.