por R G hace 15 años
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Finish Rotavirus
All age groups
Highest attack rate?
12 hrs - 3 days
Tissue culture
Median duration of viral excretion: 20 days
Symptoms indistinguishable from Rotavirus-induced gastroenteritis except disease is milder
CAVEAT: Only covers serotypes 4, 7, and 21
8-10 days
Longer than most enteric viruses
Children < 2 y.o.
Group with highest incidence
Tissue culture is gold standard for adenoviruses, but enteric adenoviruses (serotypes 40 and 41) are not detected by routine tissue culture techniques.
Molecular techniques used by research labs
Diarrhea: 5-12 days
Vomiting: 2-3 days
Otherwise indistinguishable
2nd most common cause of viral GI-tis in hospitalized patients
..cause what illness?
GI-tis
12 pentons
antennae projecting from vertices
Reoviridae
95% EtOH
Chlorinated phenols
Lysol
Rotatrix
Rotateq
Respiratory?
Water-borne
Shedding
Symptomatic, asymptomatic, or both?
Asymptomatic
Symptomatic
Fomites
DCC
DCC = Day Care Center
Nosocomial
Winter
Expensive
Not readily available
Cheap
Readily available
Outer shell necessary for attachment
11 segments
Mostly early childhood
Exception?
Norwalk virus: after 1st decade
Seasonality
1-3 days
Syllabus says "10-50 hrs"
Fecal-oral
EM
Electron microscopy
Molecular
Immunoassay
Abdominal cramps
Myalgia
Anorexia
Malaise
Headache
Fever
How does duration and severity differ?
Duration, severity is less
Particles released by death of host cell
Viral replication/assembly in cytoplasm
Hepatitis E virus
Sapporo-like virus
Snow Mountain Like Virus
Norovirus
