Prions

Lisää tämän kaltaisia

resolucion 412 /2000

luonut javier leguizamon

Medicine and Public Health from Roman Britain to c1350

luonut Anthea Pryde

Module 7: the brain

luonut Ella Etchison

han washing

luonut oscar gonzalez

Prions

caused by conversion of glycoprotein PrPc into an infectious form PrpSc

recent evidence suggests PrPc is involved in regulating cell death

Prpc located on chromosome 20 in humans

1982 Prusiner--Scrapie in sheep caused by prions

spongiform encephalopathies because large vacoules formed in brain\\

Human disease

can be hereditary but not necessarily all the time

fatal familial insomnia

Gerstmann-Straussler-Scheinker syndrome

Creutzfeldt-Jakob disease

kuru

Scrapie was reduced with proteases but not radiation which meant that the infection was a protein