Luokat: Kaikki - diagnostics - complications - pregnancy - risk

jonka Griffin Rechter 5 vuotta sitten

956

Pulmonary Embolism

Pulmonary embolism occurs when a blood clot dislodges and travels to the lungs, causing a blockage. This condition can lead to significant complications, including right-sided heart failure, reduced cardiac output, increased pulmonary vascular resistance, and respiratory alkalosis due to ventilation-perfusion mismatch.

Pulmonary Embolism

Pulmonary Embolism

Complications

DEATH
Recurrent PE
Bleeding (when on anti-coagulants)
Pleural Effusion
Organ injury: pulmonary infarction
L. heart failure
R. heart failure

Diagnostics

Wells Criteria
Malignancy +1
Hemoptysis: +1
Surgery/Immbolization w/in 1 month: +1.5
Tachycardia +1.5
Previous DVT/PE +1.5
Clinical Sxs of DVT: +3
PE is more likely than other diagnosis: +3
EKG
non specific ST and T- wave abnormalities
Tachycardia, pseudo RBBB, S1Q3T3
Imaging
(Spiral) CT / Pulmonary Angiography

Wedge-Shaped Infarct

Decreased Vascular Filling

(Compression) Ultrasound w/ Doppler

Used to find thrombi

X-Ray

Clear

1. Hamtpon's Sign 2. Fleishner's Sign 3. Westermark Sign

Labs
Other

WBC

Leukocytosis

Arterial Blood Gas

High pH, low PaCO2, low PaO2, increased A-a, normal -> decrease

D-Dimer

Increases after surgery

Highly sensitive (snout)

Pregnancy: >500 for ~ 30 days until decrease.

Treatment/Management

Management
Lifestyle Changes: exercise, stop smoking, mobility,
Vitals: Vasopressors
Compression Socks
Anticoagulants
Non-Pregnancy

Thromboectomy

IVC Filter if anticoagulants are contraindicated

3 Month minimum of warfarin

LMWH, factor Xa inhibitor, tPA (hemodynamically unstable),

Pregnancy/Breast Feeding

tPA

SubQ LMWH

IVC filter if anticoagulants are contraindicated

Clinical Presentation

Sxs
SOB, Pleuritic Chest Pain, Hemoptysis, Tachypnea, Tachycardia, Hypotension, Fever, Decreased Breath Sounds, Loud P2 (S2), Unilateral swelling, erythema, pain with dorsiflexion (Hooman's), Meyer's sign, syncope (w/ saddle emboli),
Asx

Differentials

Post Surgical Complications
MSK
MI
Congenital Defects/ Underlying Disorders
R Sided Heart Failure
Pulmonary Hypertension

Risk Factors

Previous DVT/PE
Previous Surgeries
Hypercoaguability Disorders
Immobility
Malignancy
Smoking
Long Bone Fracture
Pregnancy/OCP
Virchow's

Types of P.E.

DVT
Air
Divers/ Procedures
Amniotic
During Deliver/ Shortly After
Fat
Long Bone fx/ Liposuction/ Brazilian Butt Lift(BBL)

Pathophysiology

Decreased CO: hypotension, tachycardia, vasoconstriction
Increased PVR --> increased RV pressure --> dilation + hypertrophy
V/Q mismatch: increased dead space (V/Q>1), increased TV, RR, O2 sat, A-a gradient, HR, respiratory alkalosis
Embolus dislodges from clot due to HTN,
Pregnancy --> high estrogen levels create hypercoaguable state