Muscles

Plus de détails

Kyran and Selina Body systems

par Zhang Selina

SCH3U0

par Krish Paul - Centennial Sr PS (1506)

GRADE 6 Physical Education

par Sibulele Mambu

Muscle Actions of LE

par Sydney Guyotte

via MRf(Myogenic regulotory factor

Embryonic Myogenesis

Gastrulation

mesodermal layer

lateral plate mesoderm

paraxial mesoderm

somites

Dermomyotome

Subtopic

myoblast

myocyte

multinucleated muscle fiber

myotome

Hypaxial

epaxial

muscle progenitor cells delamine from the edges of dermomyotome

sclerotomes

vertebrae and ribs

intermediate mesoderm

axial mesoderm

Muscles

Stem cells

Satellite cells

Myoblasts

Dormant stage

Other myoblasts

Myofibres

Muscle fiber

Sarcolemma and basal lamina

Myonuclei in postnatal skeletal muscle tissue

Structure

Epimysium

Perimysium

Endomysium

Single muscle fibers

Myofibril

Sarcomere

Actin fillament

Z disc

I band

H band

A band

Mysosin fillament

protein degradation

transcription factors

NF-kB

inflammatory cytokines

MuRF-1 activity

FOXO

mTOR

protein synthesis

Atrogin-1 activity

muscle atrophy

Protein synthesis

Myostatin-Smad3 pathway

mystatin actavin A

ACVR I/II

Smad 3 activity

negative regulator

Follistation

IGF1-Akt-mTor pathway

IGF-1

Pl3K

Akt

mTOR activity

muscle growth

muscle hypertrophy

positive regulator