da Chan Samuel mancano 16 anni
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Syphilitic Gumma
TB nodule
Amorphous eosinophilic central zone
Develop necrosis in central area
Surrounded by collar of mononuclear leukocytes
Aggregation epithelioid macrophages
Eiptheloid and giant cells encompass the FB
Forms when material too large to be phagocytosed by a single macrophage
Activation of T lymphocytes release cytokines
IFNy transforms macrophages into epithelioid and giant cells
IL-2 activates more T cells and perpetuates response
Macrophages engulf particles and present to T lymphocytes
Caused by insoluble particles that induce cell mediated immune response
Beryliosis
Sarcoidosis
Crohn Dz
Brucellosis
Leprousy
TB
Few neutrophils present
Eosiniphilic meshwork of threads or amorphous coagulum
Associated with injury to membrane lined cavities
Peritonitis
Pericarditis
Occurs when exudate has a high plasma protein concentration
Densely cellular exudates of neutrophils, cellular debris and edema
Pyogenic Bacteria
Bacterial meningitis
E.g. Acute appendicitis
Skin Blister
Vascular dilation
inflammatory infiltrate
Fibrin
Liquifactive Necrosis
Neutrophils replaced by mononuclear leukocytes as chronic inflammation starts
Abscess encapsulated by granulation and fibrous tissue
Necrotic Slough