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Cells and organs of the immune system

da Nutsaba Srirat

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da Nicholas Cheng

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da Stephanie Allen

Organigrama

da RAQUEL LINARES RODRIGUEZ

lymph

lymphoid organs

secondary (peripheral)

bone marrow

post natal

MALT

lymph node

spleen

blood supply

splenic artry

trabecular artry

central artry

penicillary artrioles

sheathed artrioles

terminal artrioles

splenic cord

splenic sinus

venules

trabecular veins

splenic vein

portal vein

hematological

storage of blood in animals

hemopiosis in fetal

destroing old erythrocytes

immutological

anti-bodies formation

B cells proliferation

T lymphocyte proliferation

pulp

red

parts

splenic cords

satellet cells

to prevent coagulation of blood by isolating type 3 reticular fibers from the blood

extravasted blood

reticular fibers type 3

splenic sinuses

coated by basal lamina

discontineous

endothelial cells (fusiform)

spongy

marginal zone

functions

B cells activation

T lymphocyte activation

macrophages attack macro-organism

megration of B cells into white pulp

searching for antigenes

T lymphocytes

interdegitation dendritic cells

seprates white pulp from red pulp

white

B cells

push central artry to peripheral position

frequently

sorround central artry

central artry

convex

concave

helium

entry point

capsulated

largest lymph organ

primary (central)

thymus

digourgi ssyndrom

no Ca+

tetani

no T lymphocyte

infection

failur in thymus devlopment

thymic hormons

affected by

suprarenal

adrenocorticosteroid

petitury

thyroxine

gonadal

somatotropine

facilitate T lymphocyte proliferation

types

thymic humral facto

thimlin

thymopiotine

thymusin

paracrine hormon

reticular cells !

encapsulated

dens C.T

location

superior medisternum

primary organ for maturation

vascular supply

thymus artry

arterioles

cappilarry

blood thymus barrier

type 1 reticular cells

prevents T lymphocytes to contact with blood-born macromolcule

small bed

vein

structure

30-40 gram

medulla

type 6

in the middle (most common)

type 5

cytoreticolum

type 4

cortico-medullary junction

T lymohcytes only

cortex

cells

MHC

APCs

reticular cells

type 3

in the cortico-medullary junction

type 2

dismosome junction

in the medle

type 1

ocloding junction

in the border of trabecules and capsule

macrophages

T lymphocyte

2%

to medulla

98%

phagocitosied by macrophages forming tingble body

two lobs

devided by trabecules into lobules

bone maroow

postnatal

prenatal

liver

function