Categories: All - interventions - suicide

by Moshe Atlas 4 years ago

167

NSSI (Hasking et al. 2016)

Nonsuicidal self-injury (NSSI) in preschoolers appears more common than previously thought, with studies indicating higher rates of suicidal ideation and behaviors in this age group.

NSSI (Hasking et al. 2016)

NSSI (Hasking et al. 2016)

NSSI intrapersonal

Impulsivity

Behavioural/ computerised measures suggest that no

Self report suggests that yes (more self-critical?)

NSSI - SC/ dependency
NSSI-Perfectionism
My bottom line: This effect is probably associated with the ER models described above. Is perfectionism the source of emotional cascades and avoidance? Or perhaps perfectionism is itself an avoidance behaviour? Fascinating question!
Findings (Egan et al., 2011)

socially prescribed perfectionism predicts self-harm

To avoid difficult emotions (Emotional regulation deficits)
5 emotion regulation models

emotional reactivity (Hasking et al. 2016)

low positive reactivity has a stronger association with NSSI than negative emotion reactivity (Gratz et al., 2006 - Is Allen & Hooley, 2015 related)?

emotional reactivity is associated with NSSI (but not hen physiological laboratory methods are used)

most naturally feeds into mindfulness based models

more easily aroused + greater aroused intensity

Experiential avoidance model (Chapman et al., 2006)

MY BOTTOM LINE: This has much in common with the previous model. The root of the problem is the inability to experience challenging emotions. This model adds expressly continued by explaining how NSSI is recruited to solve the problem, and how it can become a habit.

especially high amongst individuals with comorbid NSSI and ED

higher avoidance amongst NSSI than controls (both clinical BPD and community)

NSSI can become a classically conditioned response to difficulty

NSSI focuses attention away from the emotions

the need to avoid experiencing difficult emotions

difficulties in emotion regulation model (Gratz & Roemer, 2004)

MY BOTTOM LINE:

There's nothing wrong with aroused emotions and response-focused strategies if behavioural suppression is accompanied by the acceptance of powerful emotions and their accompanied physiological arousal. If difficult emotions don't result in distress, it is logical that dramatic actions such as NSSI are less necessary.

mindfulness moderates relationship between depression and NSSI

This is over and above the effects of mindfulness on becoming depressed in the first place

Choosing a behavioural response: two keys

flexibility/ situational appropriate strategy

impulse control

Acceptance of emotion - two keys:

acceptance of emotions

awareness and understanding of emotions

Emotional cascade model (Selby & Joiner, 2009)

many studies have found an association between rumination and NSSI

Some complication with distinction between brooding and reflection (what it means + relationship with NSSI)

Emotionally challenging moments can be tolerated, but repetitive rumination and re-experiencing of these moments can cause great distress.

Process model (Gross, 1998)

MY BOTTOM LINE

This is a cognitive (and behavioural) model emphasizing the importance of the correct perspective and interpretation of events. It makes sense that experiencing strong negative feelings results in distress and a search for means to reduce that stress.

RESEARCH

CR is negatively associated with NSSI

NSSI patients report emotional distress

cognitive reappraisal is negatively associated with distress, emotional suppression can exacerbate it

response-focused

emotional suppression

Antecedent (pre-arousal)

cognitive change

attentional deployment

this can include attentional biases

situation modification

situation selection

5 stages in the process of emotional arousal

NSSI Theories (general)

4 models in Itzkowitz 2015
psychodynamic
self-punishment

NOTE: does this relate to the affect regulation and environmental models, or is it discreet? Klonsky et al. 2015 load this factor onto the intrapersonal factor, suggesting this has to do with affect regulation

relates to perfectionism and self criticism

relates to childhood emotional abuse

environmental

synonymous with interpersonal (see Klonsky et al., 2015; Taylor et al., 2018)

affect regulation (see intrapersonal below in detail
Why NSSI and not drugs or some other escape?
Cognitive-Emotional model of NSSI (Hasking et al., 2016). Emphasis on points 4 and 5 (beliefs about NSSI)

association between outcome expectancies, self-efficacy and NSSI

5. self-efficacy: belief in the anility to implement the self-injury

4. outcome expectancy: the belief that NSSI will provide relief

3. Negative self-schema: the way one views oneself (mediates the transition between negative emotional episodes and accumulated/ psychopathological negativity).

2. Poor emotional regulation abilities

see above for models/ competencies

1. High emotional reactivity

but why/ moderators/ mediators

Social cognitive theory (Bandura, 1997; Hasking et al., 2016)
self-efficacy expectancies: the expectation that one is capable of successfully implementing a chosen behaviour

trait-specific self-efficacy

JOINER, 1999

suicide requires self-efficacy for implementation

a more powerful predictor of behaviour

central to relapse, and prevention of subsequent episodes once a behaviour takes hold

general self-efficacy

the ability to handle situations as they arise. Stressful situations, or socially challenging environments may be especially relevant to NSSI.

outcome expectancies: the expected desirability/ outcome of the behaviour (based on direct or observed past experiences)

Theory

maintaining or manipulating emotional states is a central function of NSSI (expecting to achieve that emotional outcome is thus fundamental)

strong association between positive outcome expectancies and indirect harmful behaviours (eating, alcohol, smoking)

Treatment

no evidence-based successful treatment (perhaps due to lack of targeting underlying processes) - Fox et al., 2015
perhaps target perfectionism (Egan) / SC (Itzkowitz)
will differ in line with NSSI function (Taylor et al., 2018)

Preschoolers

Dervic & Oquendo, 2019
interventions include cognitive targeting guilt and medication when necessary
three points on Luby et al'. study

NSSI is a big predictor for suicide. Red flag

Preoccupation with death important to distinguish between NSSI only children and NSSI + SI

2. no association with parental mood disorders, unlike previous research

1. higher prevalence of SI an SB than previously reported

parent report

MDD sample

even though population prevalence is low, clinical professionals will meet them
Luby et al., 2019

all depressed

relies on parent report

largely caucasian

all treatment seeking

Findings

very small effects for

NO DIFFERENCE IN IMPULSIVITY

more violent life events

(look at CI - could be quite a large effect)

perhaps family history of bipolar (missed signficance)

higher externalising symptoms

higher irritability/ temper

increased depression severity

(remember all were depressed or almost depressed in the whole sample)

the sample was N (314), 26 subclinical and 288 with MDD

64.6% None

15.9% NSSI

anyone with NSSI and SI was upgraded

this messes up NSSI v other group matches

19.4% suicidal ideation

1.6% of sample had attempted

5.4% of sample also reported NSSI

(So NSSI = 21.3% of sample)

this messes up comaprisons

64% male, 72.6% Caucasian, mean age 5.15
children recruited for a depression intervention research

children on medication excluded

the healthy controls are therefore not typical healthy controls

one community sample reported a prevalence > 7%
on the up (50% increase over the past 20 years)

Prediction

Fox et al., 2019
CONCLUSION:

findings support that there is no one causal pathway. a complex adaptive system

these models are the way forward

within the context of the model, the most powerful predictor was number of self-cutting incidents in past month. BUT PREDICTION WAS VIRTUALY IDENTICAL WHEN THIS WAS REMOVED.

suggests no singular recipe for predicting the DV

high sufficiency, low necessity pattern = complex adaptive system. thought to be widespread in psychopathology.

NOTE. this does not represent a linear relationship between the IV and DV

compared univariate prediction with multivariate prediction with forest plot

forest plot

over 90% specificity, over 75% sensitivity

multivariate

a bit better than chance

univariate

chance sensitivity and specificty

39 predictor variables

4 (2*2) test of stimuli (positive/ death)(explicit/ implicit)

11 past suicide

7 past (intent) NSSI

12 cognitive/ emotional

6 demographic

past year suicide attempt - or 2 cutting episodes in past 2 weeks - or frequent suicide ideation in past 2 weeks

specific focus on cutting

not very generalisable - this does not predict onset

moderator

1021 participants recruited from online psychopathology (Which?)/ suicide forum

68% suicide attempt

96% with suicide plans history

88% with lifetime NSSI history

does this generalise to community samples?

short-term follow-ups at 3, 14, and 28 days
Machine learning algorithm to consider complex relationships (interactions, non-linear) between the many predictors (e.g. Fox et al., 2015).

random forest model

Fox et al., 2015
key

look out for suicide ideation - strong association

studies look at risk factors for continued NSSI, but not for the onset

no standardised definition of the severity of self-harm necessary to be considered NSSI

many binary IV measures of past NSSI allowed one instance to be included

this may not apply to short-term prediction, which is the norm in clinical settings

see moderators

moderators

Once moderators included and then trimmed for publication bias, very small effects in some populations

altogether 52% of variance explained by moderators

binary IV measures were stronger predictors (1.5 times more)

harder to predict in adolescents than adults (1.5 times)

this may be due to more binary DVs in adolescents

harder to predict in general population than in clinical samples. Easiest in past-NSSI group

continuous DV measures had better prediction scores (1.5 times more)

Once corrected for publication bias, overall risk factor OR = 1.16 (1.10, 1.24)
large amount of heterogeneity - therefore CI are most relevant
2/3 used a binary NSSI outcome.
central tendency of follow-up was 1-2 years
blend of clinical and community samples (and a minority with past NSSI history)

was this included as a moderator?

5078 participants (blend of adult and adolescent)
Meta-analysis of 168 predictor variables on NSSI
Itzhaky et al. (2015)
limitations

BOTTOM LINE. no evidence for specificity. See Fox et al. 2019 (this is too simplistic - they are already inpatients here!)

a binary DV. (If a continuous DV is used, better prediction is possible (Fox et al., 2015)

This is explanation and not prediction (see Fox who cites Yarkoni & Westfall, 2017)

See Zelkowitz et al., 2018 - meta-analysis

in community samples

36 (25,45)

in clinical samples

47 (33,59)

The two samples here also show this - the correlation was almost double in the second sample

NSSI has been predominantly associated with BN/ purging (See Zelkowitz et al., 2018). This sample was predominantly AN. Nevertheless there was still a strong comorbidity. Questions about generalisability of findings. The high rates in this sample raise similar questions.

inpatients with comorbid EDs

different social factors?

high comorbid MHDs

only young adolescents

almost entirely female

Regression on specific functions of NSSI

for positive reinforcement interaction between SC and dependency

if both are high then no NSSI (perhaps issues with self-efficacy)

for 3 functions no significant prediction

suggests that there is overlap in motivations amongst all NSSI users

Regression of depression, SC and dependency on NSSI (2 or more incidents in past 12 months)

In the second sample

NSSI and SC correlation = .65

63% specificity

adding in suicidal ideation improves to 88% specificty

90% sensititvity

In the first sample

NSSI and SC correlation = .39

33% specificity

98% sensitivity

Functions (Taylor et al.)

Key findings
emotion regulation most common
intrapersonal more common than interpersonal
Subtopic
Prevalence (meta-analysis)
predominantly females
large between-study variability (over and above SE) as a result of

FASM measure (lowest)

most likely because rarely was not considered endorsement

ISAS measure (higher than FSAM) - double!?

adolescent populations (higher) v others

STUDIES WITH YOUNGER CHILDREN SHOWED SMALLER ENDORSEMENTS. TAKE A LOOK!
frequency is not included. it could be that those who endorse minority function do in fact injure themselves more repeatedly and or severely
Likert type scales were reduced to dichotomous measure - this may disguise the true picture.
only quantitative data included
range of age-groups, and setting (clinical/ non-clinical)
forensic and military populations excluded
understanding that many NSSI patients have multiple motives, so not intrapersonal comparisons
a priori decision on which motives to measure
supported in factor analysis
Not like the Nock 4 factor model (used by Itzhaky, 2015)
Klonsky et al., 2015
Two factor model
Interpersonal

punish others

exert influence over others

communicate distress

Intrapersonal

self punishment

emotion regulation

Transdiagnostic

often comorbid with other psychopathology, but is not an essential symptom of it
can exist in the absence of other psychopathology

Construct

Between 1 in 5 and 1 in 8 adolescents and young adults engage in NSSI
Definition: Itzhaky 2015
socially unacceptable
repetitive
Definition: Taylor et al., 2018
deliberate damage to the body, without intent to die