Kategorier: Alle - distribución - exposición - eliminación - biotransformación

av ERICK GUILLERMO ROMERO CHASI 4 år siden

870

Fases de la acción tóxica

Las fases de la acción tóxica en el cuerpo humano incluyen una serie de procesos complejos que determinan cómo una sustancia química afecta al organismo. La absorción es el primer paso, donde la sustancia atraviesa las membranas y entra en el sistema vascular.

Fases de la acción tóxica

Fases de la acción tóxica

Type in the name of your organization and press Enter.

TOXICOCINÉTICA

The question that investors will ask is How will you turn your forecasts into reality?
Having identified your product or service, and the demand for it in the market, how will you reach that market?

Circulación

Describe exactly what customers will buy, how they will buy it, how it will be provided or delivered, and how it will be supported after purchase.
Think about:

Órgano blanco

What campaigns are you planning to publicize your product or service? Examples include:

Vía de entrada

List the ways that you can reach your market segments. Examples include:

Toxico libre o unido a proteínas

Add a description of your market research.
What market research have you done to identify the best routes to market for your particular segment?

EXPOSICIÓN A UN AGENTE QUÍMICO

How will the operations of your organization need to change, to support this plan?
Investors will need to know that you will also have the capabilities to deliver it, sustain it and scale it up.

Sin cambios

Add staff, knowledge or skills.

Metabolitos

Add a development project.

Process

What new processes will you need to establish? Do you need to change existing processes?
Processes include:

Add a process.

Tóxico libre
Acumulación

What new equipment and tools will you need? Will you replace old ones, or extend your capacity?
Add capital equipment.

Tóxico Ligado

How will your facilities need to change to implement your plan?
Will you need new premises or changes to existing premises?
Add a facility.

FASE TOXICODINÁMICA

If you win the investment or support that you need, where will you start?

Efecto tóxico
Risk

Add a risk.

Interacción tóxico-receptor
Next step

Add the next step.

FASE TOXICOCINÉTICA

You will need credible forecasts of profitability and strategic benefits if you are proposing investment in your business.

Eliminación
Los dos principales órganos de eliminación de fármacos son el hígado y el riñón. En el pa-ciente intoxicado lo es también el tracto gas-trointestinal.

Your breakeven analysis should show the minimum level of achievement that is still survivable. If operations go below breakeven, then you will need to take evasive action. Make forecasts for:

Bioacumulación
Es el proceso de acumulación de sustancias químicas en organismos vivos de forma que estos alcanzan concentraciones más elevadas que las concentraciones en su medio o en los alimentos.

Your profit and loss (or income) forecasts should detail where, when and how profitability will be achieved.
Add a highlight from your Profit and Loss forecast.

Consider making forecasts for year 1, year 2 and year 3 of your plan.

Transformaciones químicas en la estructura original por acción de procesos metabólicos microsomales o no microsomales.

How will your balance sheet change as a result of this initiative?

Add a key point from the balance sheet forecast.

Distribución
Es el mecanismo mediante el cual el tóxico llega a su sitio de acción. Depende de mecanismos tanto de la sustancia como del organismo

How will your costs base change as a result of your initiatives? Think about:

Add a key point from the costs forecast.

Es el transporte de una sustancia (translocación) a través de las membranas y compartimientos del medio exterior al lecho vascular.

How will sales increase as a result of your initiatives? Think about:

Add a key point from the sales forecast.

FASE DE LA EXPOSICIÓN

It must be clear to investors what you are asking for, when you need it and when & how it will be repaid - in short, what value they will get for their investment.

Disponibilidad química en el ambiente

Excreción

Investors will ask: how well do you know your customers and your market? Your business plan should show that you are targeting your market by well-defined segments and are focused on creating value for customers.

Eliminación por tracto gastrointestinal
no absorción del toxico ingerido

Add an organization that can compete with you, either now or in the future. Think about all alternatives that the customer may have, including doing nothing or addressing their problem in a completely different way.

Strategies

Strategy

How will you compete effectively?
Add an element of your competitive strategy. Think about:

Weaknesses

Weakness

What do the competitors do that is less attractive than your product or service?
Do they have:

Excreción Intestinal

Strength

What do the competitors do that is more attractive than your product or service?
Do they have:

Excreción Biliar

Describe the competing product or service

Eliminación por vía renal
Los agentes tóxicos polares son hidrosolubles

Who are your customers? Add a target customer segment. Groupings might include:

Reabsorción tubular pasiva

Solutions

What solutions are you offering for customers in this segment? What value do you create for them?
Add a solution.

Ph del medio

Needs

What are the needs and interests of the customers in this segment? What do they value? How do they select their purchases?
Add a customer need.

Concentración de agente toxico en plasma

Pain points

What problems and pain points do the customers in this segment face?
Add a pain point.

Gasto cardiaco

Profile

What is the characteristic of the customers in this segment?
How do you identify your potential customers?
Add a characteristic of the future customer.

Filtración Glomerular

Size

What is the estimated size and value of this segment?
What proportion of the segment is potential customer for you, taking into account competitors, market maturity and demand?

Otras vías de eliminación
Líquido cerebro espinal; leche sudor y saliva

What market position are you aiming at?

Think about:

Vías Respiratorias, Renal y Biliar
About the industry

Add some key points about the industry you are working in.

Biotransformación

Describe the vision and the opportunity that the plan is based on.
The investor's question you answer here is Where are you headed, and why?

Membrana celular, receptores específicos
Endocelular y acción sobre el ribosoma

Where do you want to be in 5 years?
Where would you like to be in terms of:

aumento de la polaridad
hidrosolubles

Where do you want to be in 12 months? Where would you like to be in terms of:

Acción final
oxígeno al tóxico invasor

Add a key point about your Unique Selling Point. Your USP is what will lead marketing, and help customers to choose you over alternatives. In comparison to the alternatives, why will your product or service...

Fase II o Síntesis
Conjugación Glucurónica, sulfo,etc

Add a key point about your strategy.

How does this opportunity...

Fase I o Presíntesis
oxidación, reducción, hidrólisis

Add a key point about the opportunity that you are pursuing.

Distribución y Almacenamiento

Provide your investors with a clear picture of your business: how it is structured, who owns it, who runs it, and how it is doing so far?

Barrera hematoencefálica
Liposoluble

Add some information about the values and principles of your company.

Proteínas plasmáticas, Hígado y Riñón
Tejido adiposo, Tejido Óseo

Add some information about your successes and achievements. Think about:

Transporte
Proteínas plasmáticas, eritrocitos. libre en plasma

Add some information about important partnerships. Think about:

Almacenamiento
forma inerte

Who are the key members of your management team, and what are their skills and experience?

Organismo
permeabilidad del endotelio

Summarize the record of your credit history.

PH de los líquidos corporales

Add some information about your current profitability.
For example:

circulación sanguínea regional

Add some information about the current shareholding.
How much have the current owners invested in the business?

Gasto cardíaco

Add some information about the capital finance situation at your company.

Tropismo

Add some information about the regulatory environment that affects your company. Apart from company law, what other regulations apply to your sector? Consider:

Tóxico
grado de unión a las proteínas plasmáticas

Add some information about the governance of your organization.

Ácidos y bases, Reacción covalente, alkilantes, radicales libres libres

What is the legal status of your organization? Are you a sole trader, a limited company with shareholders, or a non-profit?

Absorción

Although the executive summary appears first in the document, it is easier to complete it last, when you can summarise and prioritize the key points in your plan.

Propiedades fisicoquímicas
INTESTINO

List the benefits that will come from pursuing this opportunity. Include:

Distancia de translocación
PIEL

List the financial aid and other support that you are seeking, so that you can take advantage of this opportunity.

Fagocitosis y pinocitosis
ALVEOLO

Briefly summarise the opportunity that your plan describes, and why it is strategic for your company.

Difusión facilitada
hidrolisis

Add the key points about the track record of your team and your capabilities.

Transporte activo
coeficiente de partición

Add short descriptions of the key products and services which bring your mission to life and are making it happen.

Difusión pasiva
volatilidad

Summarise the value and the difference that your organization aims to create. Mission statements are more useful if they describe the difference that you want to make to your customer's lives, rather than what you want to achieve personally. Your mission statement should directly influence strategic decisions.

Acumulación a los tejidos

Your business plan is a commercially sensitive document and you may wish to add a confidentiality statement (or non-disclosure agreement) at the front of the document.
Type in or attach your statement of confidentiality

Afinidad a proteínas, coeficiente de tipo hidrosoluble, fijación selectiva por afinidad química