Alzheimer's disease is a progressive neurological condition characterized by brain shrinkage, cell death, memory loss, and cognitive decline. It disrupts daily functioning by affecting concentration, decision-making, and mood.
Life expectancy post-diagnosis ranges from 3-11 years, with a highly variable progression rate.
TREATMENT
No cure. The medication increases acetylcholine levels, which helps nerve cells communicate and improves memory and thinking.
Donepezil
Rivastigmine
HISTORY
Initially classified as general dementia before the 1970s. The term "Alzheimer's" emerged in 1984, with a 1990s focus on brain damage caused by plaques and tangles.
SYMPTOMS
- MCI: Minor memory and thinking changes.
- Mild Dementia: Impaired memory, problem-solving, and behavior.
- Moderate Dementia: Significant memory loss, confusion, and daily assistance needed.
- Severe Dementia: Loss of communication, physical decline, and full-time care needed.
CAUSES
Likely due to a mix of genetic, lifestyle, and environmental factors that disrupt brain proteins, leading to neuron damage.