Spectrum of Activity

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Spectrum of Activity

Beta Lactams

Monobactams

Aztreonam

Carbapenems

Imipenem, Meropenem, Doripenem

Ertapenem

Anaerobes

No pseudomonas

No acinetobacter

Cephalosporins

Cephalosporin + Beta Lactamase Inh.

Ceftaz/Avi, Ceftol/Tazo

MDR Enterobacter

Ceftaroline (IV)

Gram Negative (HACEK)

Gram Positive (MSSA, MRSA, Strep, MRSE, NO Enterococcus)

4th Generation

Cefepime

Gram Positive (strep, MSSA)

3.5 Generation

Ceftazidime (IV), Cefiderocol (IV)

3rd Generation

Ceftriaxome, Cefdinir

Anaerobes (oral) *KAHOOT SAYS NONE*

HACEK DOC

Cefdinir NO Neisseria

Gram Positive (strep)

S. Pneumoniae DOC

2.5 Generation

Cephamycin, Cefoxitin, Cefotetan

Gram Positive (Strep A/B)

Cefuroxime

Cephalexin (PO), Cefazolin (IV)

Gram Negative (PEK)

Gram Positive (Staph, Strep, NO Entero)

MSSA DOC

Penicillins

Ureidopenicillins + Beta lactamase Inh.

Pip/Tazo

Anaerobes (oral and gut)

Gram negatives (inc. pseudomonas)

Gram positive (strep, Enterococcus)

Aminopenicllins + Betalactamase Inh.

Amp/Sulb, Amox/Clavul

Anaerobes (gut and oral)

Gram Negatives (No pseudomonas)

HIB DOC

Gram positive (strep, Enterococcus, Listeria)

Aminopenicillins

Ampicillin, Amoxicillin

Gram positive (Strep)

Enterococcus DOC (if susceptible)

Listeria DOC

Anti-staph PCN

Naf, Ox, Diclox

Gram positive (MSSA and Strep)

Natural penicillins

Pen G, Pen VK

Syphilus (Trep. Pal.) DOC

Gram Positive (Strep only)

Tetracyclines

2nd Generation

Tige, Omada, Erava

Gram negative (enteric)

1st Generation

Tetra, Doxy, Mino

Gram negative (non-enteric only)

Gram positive (MSSA, MRSA, Strep)

Macrolides

Azithromycin, Clarithromycin

Gram negative (enteric only)

Gram positive (strep)

Nucleic Acid Inhibitors

Fluoroquinolones

Delafloxacin

Anaerobes (oral, gut)

Gram negatives (incl. pseudomonas)

Gram positive (MSSA,MRSA + strep)

Levofloxacin

Gram negative (incl. pseudomonas)

Moxifloxacin

Anaerobes (Gut, oral)

Gram Negative (no pseudomonas)

Gram Positive (Strep)

Ciprofloxacin

Atypical

Aminoglycosides

Gentamicin, Tobramicin, Amikacin, Plazomicin

Gram positive (ONLY synergy)

Glycopeptides

Lipoglycopeptides

Vanc, Dapto, Telav, Dalba, Ortito

Gram Positive (MSSA, MRSA, Strep, Entero (except Dalba)

Listeria (Linezolid)

Folate Synthesis Inhibitors

Trimethoprim, Sulfamethoxazole

Gram Negative (variable)

Gram Positive (MSSA, MRSA, NO STREP)

Cell Membrane Inhibitors

Polymyxins

Gram Neg (only Pseudomonas)

Fosfomycin

Gram Negative (incl. pseudomonas)

Other

Nitrofurantoin

Gram negative

Gram positive (Enterococcus)

Metronidazole

Anaerobes (gut)

DOC B. Frag

Lefamulin

Atypicals

Gram Negative

Gram Positive (MSSA, MRSA, Strep)

Clindamycin

Anaerobes (oral)

NOT B. Frag

Gram Positive (MSSA, MSSE, MRSA(CA), Strep)