カテゴリー 全て - pregnancy

によって R G 15年前.

1069

Hyperlipidemia

Statins are commonly prescribed for individuals with cardiovascular disease to manage cholesterol levels. By reducing intracellular cholesterol, statins increase LDL receptors, thereby decreasing plasma LDL concentrations.

Hyperlipidemia

Hyperlipidemia

↓intracell cholesterol = ↑LDL receptor = ↓plasma [LDL]

Both

Niacin
Cutaneous flush, pruritis

Aspirin 30 min. prior

Triglycerides

N3FAs

Marine Oils

Gemfibrozil
↑LDL receptors on membrane
Rash
Fibrates
Interactions

Inhibits platelet aggregation

Displaces warfarin

Arrhythmia in CAD
Flu-like syndrome
Clofibrate
Fenofibrate

NOT available in the U.S. but sold in Canada

↑HDL
PPAR-alpha
↑LPL expression

Cholesterol

Ezetimibe
Blocks cholesterol absorption @ enterocyte
Niemann-Pick C1-like protein
Bile-acid exchanger
Acidic Drugs

Thyroxine

Thiazides

Tetracycline

Iron

Hydrocortisone

Vit. A,D,E,K

Phenobarbital

Warfarin

Digoxin

Side Fx

↑VLDL

GI

Tastes like sand

Pruritis a/w biliary obstruction
Drugs

Colesevelam

Colestipol

Cholestyramine

Statin

Those with CVD should be on a statin.

Pregnancy
Others

Inhibits VLDL synth.

Prava

Single day dosing

Atorva

Simva

Super-

Pitava

Rosuva

Lovastatin