Categories: All - visual - diagnosis - hypertension - obesity

by Nicholas Sostilio 9 years ago

322

Pseudotumor Cerebri

Research on pseudotumor cerebri syndrome, also known as idiopathic intracranial hypertension, highlights its correlation with obesity, particularly in pediatric cases. Studies indicate that this condition is commonly associated with females, increased body mass index (

Pseudotumor Cerebri

Citations: Paley, G. L., Sheldon, C. A., Burrows, E. K., Chilutti, M. R., Liu, G. T., & McCormack, S. E. (2015). Original article: Overweight and Obesity in Pediatric Secondary Pseudotumor Cerebri Syndrome. American Journal Of Ophthalmology, 159344-352.e1. doi:10.1016/j.ajo.2014.11.003 Clara L., A., Aley, T., & Mário Luiz Ribeiro, M. (2015). Factors affecting visual loss and visual recovery in patients with pseudotumor cerebri syndrome / Fatores que influenciam na perda e na recuperação visual de pacientes com a síndrome do pseudotumor cerebral. Arquivos Brasileiros De Oftalmologia, (3), 175. doi:10.5935/0004-2749.20150045

Pseudotumor Cerebri (Idiopathic Intracranial Hypertension)

More Information

2 Types
Secondary

Caused by medications or other preexisting conditions (Paley et al., 2015)

Primary

Idiopathic, occurs without a known cause. Currently thought to be associated with obese/overweight females. (Paley et al., 2015)

Concerns with Disease
Possible retinal hemorrhages (Clara & Ribiero, 2015)
Possible visual field loss due to papilledema (Clara & Ribiero, 2015)
Causes an increased pressure on the optic nerve resulting in permanent damage (Clara & Ribiero, 2015)

Epidemiological Data: Correlational Study by Clara and Ribiero (2015)

Results
Associated with vision loss-->86%
Associated with headaches-->80%
Associated with obesity or being overweight-->increased BMI of 32 kg/cm^2 (class I obesity)
Associated with females-->6:1 ratio (F:M)
Study Parameters
Best Corrected VA
Time from Original Diagnosis
Visual Symptoms
History of Hypertension
Body Mass Index (BMI)
Weight
Sex
50 Subjects (43 F, 7 M)

Differential Diagnosis: Must be a form of Pseudotumor Cerebri

Increased ICP without neurological findings
Major indication of PTC (Clara & Ribiero, 2015)
Possibility of some visual field loss
Patient was unable to obtain a distance VA better than 20/40 suggesting that there must be ocular disease present and possibly some visual field loss (Clara & Ribiero, 2015)
No clear indication of cause-->idiopathic
Correlational studies such as from Clara and Ribiero (2015) suggest that the cause of pseudotumor cerebri is correlated with females, obesity, hypertension, and increased BMI (Clara & Ribiero, 2015)
Not glaucoma
IOP's are within normal range (Clara & Ribiero, 2015)

Patient MRN: 111716

Lumbar Puncture
Increased Intracranial Pressure (ICP)
Findings
Vitreous Opacities

Possible Posterior Vitreous Detachment (PVD)

IOP
OS: 16 mmHg
OD: 15 mmHg
Visual Acuity
Near Aided with Spectacles

OU: 20/20

OS: 20/25

OD: 20/30

Far Aides with Spectacles and Pinhole

OS: 20/40

OD: 20/40+2

Far Aided with Spectacles

OU: 20/40+2

OS: 20/70-1

OD: 20/60-1

Family History
Mother

Hypertension

Father

Diabetes

Laser Eye Surgery for "Hole in Eye" ~20 years ago
Medications and Supplements
Iron
Vitamin D
Ferrous Fumarate (324 mg Tablet)
Valsartan (160mg Tablet)
Bisoprolol Fumarate (10mg)
Albuterol
Previous Diagnoses
Asthma
Presbyopia
Hypertension (150/95)
Sleep Apnea
Papilledema
Pseudotumor Cerebri
Chief Complaint: Flashes and Floaters
African American
49 years old
Female