Systemic inflammatory response syndrome (SIRS)

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Literature

luonut Fabio Pirri

FMCS3100

luonut Rosanna Jeffery

Eicosanoids

luonut Ramzi Garvin

CPS Mapping

luonut sabrina Brookes

Systemic inflammatory response syndrome (SIRS)

ETIOLOGY

Combination of several “insults"

Infection

Trauma

Inflammation

Ischemia

PATHOGENESIS

Preoperative Illness

Trauma or Operation

Tissue Ingury

Excessive Inflammatory Response

Inadequate Resuscitation

SIRS/MOD

Optimal Oxygen Therapy

Recovery

CRITERIA (When any 2 or more of these are observed at a time SIRS is confirmed)

Heart rate >90 beats per minute

Fever >38◦C or < 36◦C

Abnormal white blood cell count (>12,000/mm3 or <4,000/ mm3 or >10% bands

Respiratory rate >20 breaths per minute or PaCO2 <32 mm Hg