TREATMENT OF DM: ORAL HYPOglycaemics

Mai multe ca aceasta

COWS

după Pablo Rollán

33A Michelle D. 3036 (SPLIT 16A)

după Cortez Quarles

เคสกลุ่มผู้ป่วยหญิงไทย เสร็จ

după Pefch ลงงาน

Diabetes

după John Rodgers

TREATMENT OF DM: ORAL HYPOglycaemics

Alpha GluCOSidase Inhibitors

BIGuANIDES

Prandial Glucose Regulators (PGR)

SulphoNYLureas

S.Es

Secondary failure rate = 5-10% per yr

Hypoglycaemia

WEIGHT GAIN by increasing inulin secretion

Shud not give glibenclamide & chlorpropamide (=long-acting) 2 over 70s if live alone - fatal

Effective, well-tolerated & widely used

No lag period b4 response

High initial response

INCREASE insulin secretion

Examples:

ChlorPROpaMIDE

TolBUTAmide

GliPIzide

GliCLAzide

GliBENclaMIDE

ThiaZOlidiNEdiones (GlitaZONES)