TREATMENT OF DM: ORAL HYPOglycaemics

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CHAPTER 8 - PRINCIPLES OF QUESTIONNAIRE CONSTRUCTION

от Cary Chicaiza

dieting

от Delories Spears

லேப்டாப்

от Ram J

THE FLIGHT

от Maria Fernanda Mite Reyes

TREATMENT OF DM: ORAL HYPOglycaemics

Alpha GluCOSidase Inhibitors

BIGuANIDES

Prandial Glucose Regulators (PGR)

SulphoNYLureas

S.Es

Secondary failure rate = 5-10% per yr

Hypoglycaemia

WEIGHT GAIN by increasing inulin secretion

Shud not give glibenclamide & chlorpropamide (=long-acting) 2 over 70s if live alone - fatal

Effective, well-tolerated & widely used

No lag period b4 response

High initial response

INCREASE insulin secretion

Examples:

ChlorPROpaMIDE

TolBUTAmide

GliPIzide

GliCLAzide

GliBENclaMIDE

ThiaZOlidiNEdiones (GlitaZONES)