Kategorier: Alla - insulin - response - weight - medication

av SHAMIM IQBAL för 17 årar sedan

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TREATMENT OF DM: ORAL HYPOglycaemics

The document outlines various oral hypoglycemic treatments for managing diabetes mellitus (DM), detailing different classes of medications such as biguanides, thiazolidinediones (glitazones)

TREATMENT OF DM: ORAL HYPOglycaemics

TREATMENT OF DM: ORAL HYPOglycaemics

Alpha GluCOSidase Inhibitors

BIGuANIDES

Prandial Glucose Regulators (PGR)

SulphoNYLureas

S.Es
Secondary failure rate = 5-10% per yr
Hypoglycaemia
WEIGHT GAIN by increasing inulin secretion
Shud not give glibenclamide & chlorpropamide (=long-acting) 2 over 70s if live alone - fatal
Effective, well-tolerated & widely used
No lag period b4 response
High initial response
INCREASE insulin secretion
Examples:
ChlorPROpaMIDE
TolBUTAmide
GliPIzide
GliCLAzide
GliBENclaMIDE

ThiaZOlidiNEdiones (GlitaZONES)