TREATMENT OF DM: ORAL HYPOglycaemics

More like this

Does the modern technological world do more harm than good to the human body?

by Brock Spence

33A Michelle D. 3036 (SPLIT 16A)

by Cortez Quarles

The 1920's & 1930's

by Claire Gallagher

Sample Mind Map

by Daniela Cortes

TREATMENT OF DM: ORAL HYPOglycaemics

Alpha GluCOSidase Inhibitors

BIGuANIDES

Prandial Glucose Regulators (PGR)

SulphoNYLureas

S.Es

Secondary failure rate = 5-10% per yr

Hypoglycaemia

WEIGHT GAIN by increasing inulin secretion

Shud not give glibenclamide & chlorpropamide (=long-acting) 2 over 70s if live alone - fatal

Effective, well-tolerated & widely used

No lag period b4 response

High initial response

INCREASE insulin secretion

Examples:

ChlorPROpaMIDE

TolBUTAmide

GliPIzide

GliCLAzide

GliBENclaMIDE

ThiaZOlidiNEdiones (GlitaZONES)